Prof. Padhu Seshaiyer is a tenured full Professor of Mathematical Sciences at George Mason University and works in the broad areas of Computational Mathematics, Computational Data science, Mathematical Biology, Computational Biomechanics, Design Thinking and STEM Education. In particular, his research includes the development of efficient analytical and numerical techniques and computational algorithms including predictive AI based approaches to solve real-world challenges. During the last two decades, he has initiated and directed a variety of educational programs including faculty development, post-graduate, graduate and undergraduate research, K-12 outreach, teacher professional development, and enrichment programs to foster the interest of students and teachers at all levels to apply well-developed research concepts, to fundamental applications arising in STEM disciplines. In Oct 2020, he was invited to take part in Prime Minister Modi's Vaibhav initiative that helped to bring Indian origin luminaries in academic institutes and research and development (R&D) organizations across the world and resident counterparts on a single platform to discuss the future of data science education as a part of India's vision on AI for the future. He has also been a champion for creating new initiatives to help bridge post-secondary transitions to colleges and universities for students to gain necessary skills and competencies in scientific computing, AI and Data Science related fields that is driven by the workforce needs. Over the years, he has won several prestigious awards and honors for his contributions to research, teaching and service.